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Indeed, while essential metals, such as iron or zinc, have been found to be altered in several respiratory diseases, the exact causes and mechanistic consequences of this metal dysregulation on the immune system and respiratory microbiota still need to be further explored (242)

10.3969/j.issn.1000-484X.2020.03.007 103 YangL
Genetic screening of cells that are resistant to GPX4-inhibiting drugs suggested that ACSL4 and LPCAT3 are essential for ferroptosis triggered by the suppression of GPX4 activity [37]

Further, alcohol induces BBB dysfunction and neuroinflammation through MMP-3/9 activation and angiogenesis (VEGF)-A/VEGFR-2) impairment in primary endothelial cells in the brain (Muneer et al., 2012)
Verticillium dahliae chromatin remodeling facilitates the DNA damage repair in response to plant ROS stress

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