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CAFs can promote tumor growth and angiogenesis through the release of certain growth factors and proteases

To visualize similarities and differences between the samples, S-plots of data pairs of accurate mass and retention time of each metabolite were calculated based on orthogonal partial least squares discriminant analysis (OPLS-DA)

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Within cancer cells lactate is the primary substrate for TCA cycle activity as well

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

10.1089/jwh.2008.1193 62