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Br J Pharmacol 180(3):308329

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and 0.8% of patients discontinued treatment due to side effects

The authors found that this network not only included members of the UNC-52-like kinase 1 (ULK1) complex, membrane fusion, and vesicle transport regulatory factors but also involved TRAnsport Protein Particle (TRAPP), endosome-associated recycling protein (EARP), glycoprotein A repetitions predominant (GARP), exocyst, AP-1, and AP-4 complexes

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Supportive care during the drug-withdrawal period includes fluids, antiemetics, and antipruritic agents