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He takes it because the risk-reward maths made sense to him given thin data, not because its settled science

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Study highlights Oxidative stress in sickle erythrocytes due to polymerization and auto-oxidation of HbS causes hemolysis and contributes to sickle cell pathophysiology

In the context of alcoholism, chronic acetaminophen ingestion can cause toxicity at doses that are generally safe (alcohol-tylenol syndrome)

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