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Bondar OP, Rowe ES1998Role of Cholesterol in the Modulation of Interdigitation in Phosphatidylethanols

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The current transport model for the NPC system postulates that NPC2 binds sterols in the lumen and loads them into the NTD, which transfers the sterol to a tunnel that is formed by the middle-luminal domain and C-terminal domain of hNPC1 and NCR1, respectively (1, 27, 33, 34)

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