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Mackalls group at Stanford, for example, has reported promising results from a small clinical trial of a CAR T-cell therapy in some children and young adults with a fatal brain cancer called diffuse midline glioma

Lu-177 DOTA-TATE is another approved metal-containing peptidomimetic and is used as a therapeutic isotope

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However, hemolysis, which can be considered as necrosis of erythrocytes, belongs to the so-called ACD modalities, indicating that this cell death occurs in response to physical or mechanical damage to RBCs and lacks signaling pathways [4]
McEachin et al., 2025)
