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Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N

Acts as a powerful antioxidant, effectively combating oxidative stress and promoting overall health

Its combination with trastuzumab further enhances anti-tumor activity, inducing ROS accumulation and promoting apoptosis in SK-OV3 and BT-474 cells, thereby significantly improving the therapeutic effect [111] (Table 3)

GuimaresAVenncioA

(2019) performed a randomized controlled trial involving 56 women with PCOS, revealing a decrease in hirsutism, total testosterone, hs-CRP, and MDA, alongside an increase in TAC and total GSH among participants administered 5 g of melatonin twice daily for 12 weeks, in contrast to the placebo group [186]

IMPROVED MOOD : B12 has been shown to have a positive effect on mood, helping to reduce symptoms of anxiety, depression, and stress