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The patent gives exceedingly little information about the isolation process, stating only that a variety of relatively crude chromatographic approaches were utilized (i.e., ion-exchange and gel) followed by dialysis (i.e

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This study evaluated the therapeutic potential of non-gene-edited human chemically induced pluripotent stem cell-derived neural stem cells (hCiPSC-NSCs) in a prenatal valproic acid (VPA)-induced rat model of ASD, using a dual-pathway administration strategy (intravenous systemic delivery combined with an intracerebroventricular boost)