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From 2D to 3D: novel nanostructured scaffolds to investigate signalling in reconstructed neuronal networks

Based on the geroscience concept that aging and age-related disease conditions are associated with the same pathways [2,3], resilience to aging, as measured by ability to recover from physical stress, provides a resistance environment for preventing or delaying the onset of age-related conditions

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Based on the hypothesis that agonists on mGluR Group II would suppress the spontaneous firing in auditory neurons (as has been observed during residual inhibition tasks), a drug study showed tinnitus suppression due to the application of a Group II specific agonist 56

Diaz-Castro, B., Gangwani, M