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The dose escalation in days 16-30 is designed to reinforce the signaling pathways activated in Phase 1
It is important for endocrinologists and primary care physicians to recognize that NAFLD in T2DM has been shown to be associated with adverse metabolic changes resulting in increased atherosclerotic disease and cardiovascular consequences (4,5)
Di DanieleNNoceAVidiriMFMoriconiEMarroneGAnnicchiarico-PetruzzelliMet al
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They also increase infection risk
BMJ Open 5 , e007366e007366 (2015)
