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Description
Clinical severity was graded as 0 (normal), 0.5 (erythema and edema in only one digit), 1 (erythema and mild edema of the footpad, or ankle or two to five digits), 2 (erythema and moderate edema of two joints [footpad or ankle, two to five digits]), 3 (erythema and severe edema of the entire paw), or 4 (reduced swelling and deformation leading to incapacitated limb) 68

and an antioxidant, protecting the body from free radical damage obtained from toxic metals

Fusion of the mouse IgG1 Fc domain to the VHH fragment (ARP1) enhances protection in a mouse model of rotavirus
However, this has a negative impact on the skin

Toth A, et al
6, over the course of the accelerated heat stress study, the characteristic SH and COO- peaks decrease as a function of the applied heat stress