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Apatinib combined with SOX (S-1+oxaliplatin) as a neoadjuvant therapy for advanced or metastatic GC also has demonstrated significant efficacy and safety and the common adverse reactions include leukopenia, neutropenia and hypertension

[20] analyzed 645 patients with ulnar nerve injury for 30 years and discovered only 2 injuries (0.3%) were caused by injection

10.1038/npp.2010.83 86 RoeslerR.SchrderN
All those discrepancies could be due to the different level of OR expression, the cellular models and the existence of spare receptors as previously mentioned (Connor et al., 2004)

Wijesekera LC, Leigh PN (2009) Amyotrophic lateral sclerosis