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Its metabolism is closely intertwined with the circadian rhythm, exhibiting a 24-h rhythmicity due to circadian rhythms
Although RM1 cells do express AR, others have shown that RM1 are insensitive to androgen deprivation in vitro and in vivo [74, 75], thus representing aggressive prostate cancer

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10.1080/14779072.2019.1651198 Expert Rev
doi: 10.3389/fonc.2022.961637 316 ChengXPengTChuTYangYLiuJGaoQet al
