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These are cosmetic variations only and do not affect chemical identity, purity, stability, or integrity

A novel homozygous COX6A1 variant causes axonal charcot-marie-tooth disease, developmental delays and mitochondrial dysfunction

Stathopoulos P, Kumar A, Heiden JAV, Pascual-Goni E, Nowak RJ, OConnor KC

Zinter MS, Delucchi KL, Kong MY, Orwoll BE, Spicer AS, Lim MJ, Alkhouli MF, Ratiu AE, Mckenzie AV, Mcquillen PS, Dvorak CC, Calfee CS, Matthay MA, Sapru A

While identification of the different molecular signatures and genotypes among responders and non-responders may help develop predictive biomarkers to enable patient stratification in clinical setting, the molecular and genetic heterogeneity in many tumors is still a big challenge for successful cancer therapy [182]

Determine the fraction of the dose excreted unchanged from this drug in the urine