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On top of that, it weakens sirtuin activity, which disrupts essential cell maintenance and speeds up epigenetic drift

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This DA signaling mechanism in the BLA not only facilitates the normal sleep cycle but also contributes to the occurrence of cataplectic attacks in narcoleptics, illustrating its significance in both physiological and pathological aspects of sleep regulation ( Our analysis of dopamine and glutamate levels provides insights into the neuroprotective and cognitive effects of the treatments

They might be caused as a result of structural and chemical changes in the brain