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Glutathione production declines with age and other factors such as poor nutrition, increased use of acetaminophen (such as Tylenol), NSAIDS and statins, alcohol consumption, environmental toxins, and stress

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High ROS level damages cellular DNA [8], proteins [9], and lipids [10], which promotes genomic instability and oncogenesis
( G ) Individual metastatic cell lines (n = 3) were generated to express each shRNA once and subjected to soft agar assay in ( G ) for n = 3 replicates

2020;48(D1):D32834

Z., Patil, R