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The exact mechanisms linking PD and ED are not fully understood, but several factors may contribute to these findings (Figure 2)

it decreased total aortic lesion area, although lesion burden in the aortic sinus was not altered [81]

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Proteins that have undergone lactylation are inclined to engage in the modulation of neuronal activity, which can exacerbate neuronal damage and lead to impaired brain function [46]
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