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Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase

thus, understanding the mechanisms behind this resistance can significantly improve treatment efficacy and patient outcomes [177]

Drugs 81 , 495501 (2021)

doi: 10.4049/jimmunol.174.11.6820 86 DengJLiuYYangMWangSZhangMWangXet al

Luthione is medically indicated for the prevention of neurotoxicity resulting from cisplatin-based or similar chemotherapeutic regimens
