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Starting around 2 months of age, we observed significant barbering in female mice leading to alopecia in the K408R mutants (Fig

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These approaches enable systematic analysis of immune cell dynamics, cellcell interactions, and pathologic microenvironments within tissues, leading to a more comprehensive understanding of inflammatory phenotypes (Figure 6B) ( in silico pre-screening of natural products, with top candidate compounds subsequently validated in human organoidzebrafish chimera models

Endogenous and exogenous sources of free radicals in biological systems Free radicals in biological systems may originate from either extracellular or intracellular sources (Aranda-Rivera et al