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glutathione peroxidase a selenoenzyme Effects of selenium and on the biosynthesis of prostaglandin E₂ and F₂α by the ram vesicular gland Simplified catalytic mechanism of the
Description
Under cysteine-limiting conditions, cells depend on the uptake of extracellular cystine, subsequently reduced to cysteine in the cytosol

It may prevent the binding of the FOXO4 protein with p53, allowing p53 to bind with DNA and trigger apoptosis in senescent cells

Stockwell BR, et al

Bibcode:2013PNAS..11011121L

Discovery and development of MEDI7247, a novel pyrrolobenzodiazepine (PBD)-based antibody drug conjugate targeting ASCT2, for treating hematological cancers

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