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Description
Elevated NAD+ levels activate sirtuins, particularly SIRT1, which are NAD+-dependent deacetylases that regulate numerous metabolic processes including fat oxidation, glucose metabolism, mitochondrial biogenesis, and cellular stress responses
Ortgies, S
& Wanchu, A
In addition, macrophages can either store iron, mostly complexed with ferritin, or released a free fraction in the cytoplasm, known as the labile iron pool (LIP)
Therefore, the antioxidant defense system could be a target to weaken C
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