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Brazil), FNRS (Charg de Recherche), and ULB

In addition to inhibiting NF-kB signaling, riboflavin can also inhibit critical components of the non-canonical inflammasomes, such as caspase-1 activity 47 , either via the AIM2 cytosolic innate immune receptor, which recognizes double-stranded DNA (dsDNA) released during cellular perturbation, or via the Nod-like receptor NLRC4, which recognizes bacterial ligands such as flagellin and the type three secretion system (T3SS) 47

Neuron 97 , 742768 (2018)

10.1016/j.ejpb.2024.114513 239

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It sits in this weird, unique place