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2005 Nov 18;337(2):739-45

Olanow CW, Goetz CG, Kordower JH, et al

Nicotinamide, NAD(P)(H), and methyl-group homeostasis evolved and became a determinant of ageing diseases: hypotheses and lessons from pellagra

Adult stem cells in the small intestine are intrinsically programmed with their location-specific function

The magnitude of the increase is even larger than that of the preceding housing boom, from first quarter 1998 to second quarter 2007

They further determined that DISC1 regulates activation of the Rho-GTPase RAC1 in the PSD, RAC1 being a protein whose activity modulates spine shape through regulation of actin dynamics (see discussion below)