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If no improvement appears after six months of consistent use, consider whether the protocol needs modification

According to NICE guidance (NG49) , patients with NAFLD should undergo risk stratification for advanced fibrosis

The effects of ANP on lipolysis are more relevant to primates than rodents, as rodents express over 100 times the level of the clearance receptor NP clearance receptor (NPCR), which mitigates the effect of ANP on lipolysis (112, 113)

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Recommendation: Pharmaceutical semaglutide/tirzepatide can last 30-45 days
