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There is evidence that ELA exposure is associated with epigenetic changes in the immune system and the functioning of the hypothalamic-pituitary adrenal (HPA) axis, which modify and determine the stress response[47]

The role of ozone treatment as integrative medicine

It is proposed that an autoimmune response is triggered by B burgdorferi similar to responses that occur after chlamydia or strep throat

[DOI] [PMC free article] [PubMed] [Google Scholar] [18].Sunde RA, Raines AM, Selenium regulation of the selenoprotein and nonselenoprotein transcriptomes in rodents

Together they target the root cause of pigmentation-driven dark circles, not just puffiness