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For the most part, the benefits outweigh the risks involved

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171 Furthermore, given the chronic and recurrent nature of IBD, long-term studies are required to assess the safety and therapeutic durability of peptide-based treatments

It has been reported that tools that rely on prior knowledge in the form of spectral libraries deal better with low selectivity data than library-free tools 9 , and peptide-centric approaches perform better to exploit highly comprehensive DIA data than spectrum-centric methods 10

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