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A small number of participants were referred to the author with partial efficacy on amitriptyline or cyproheptadine, and when episodes resolved after increasing the dosage the families chose not to start one or both cofactors

Gallo L, Sarnacchiaro P

10.1038/s41575-023-00800-4 105 YuL.HongW.LuS.LiY.GuanY.WengX.et al (2022)

2000;14 Suppl 1:S31-8

Its also linked to better lipid profiles

Crucially, current evidence remains correlational
