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About the week marker I began to feel extreme fatigue

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This breaks the peptide structure

Except your dose was supposed to increase to 4mg at week 5, which means 80 units from the same vial

Vascular effects include the enhanced production of several vasoconstrictors from endothelial and mesangial cells, such as endothelin-1, platelet-activating factor, and arachidonic acid metabolites, mainly prostaglandins and thromboxane [ 45 , 50 ]