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In addition, the fluorescent group A2E of lipofuscin is activated by blue light, releasing free radicals and causing lipid peroxidation

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Apart from these ways in which Leishmania minimizes the production of ROS and NO, it also manages to enhance the host antioxidant response by upregulating the transcription factor NF-E2-related factor 2 (NRF2) (49, 50)

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These intramuscular injections, usually containing cyanocobalamin or methylcobalamin, are administered weekly or monthly as prescribed by a healthcare provider