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We selected 44 TFs based on robust expression, motif accessibility, gene regulatory network size, target gene expression and predicted transcriptional consequences in the RG lineage (Supplementary Table 1

Defining When to Stop First-in-Human trials and dose escalation protocols are required to state the stopping rules clearly for individuals, dose escalation, and the overall study

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32 Similarly, an association between elevated homocysteine levels and cognitive impairment has been noted, but subsequent vitamin B 12 replacement does not have preventive or therapeutic benefit

Journal of Controlled Release (2000).

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