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The sulphation pathway is saturable at therapeutic doses whereas the glucuronidation pathway only becomes saturated in overdoses (see Fig

doi: 10.1016/j.jep.2023.116305 111 ZhouCHuangJLiQZhanCXuXZhangXet al
Cells 11 , 3843 (2022)

Its a synthetic peptide derived from a protective protein found naturally in your stomach

GLP-1R agonists, due to widespread receptor distribution in hypothalamic and amygdalar regions, may influence reward circuitry through dopaminergic modulation

Sun B, Luo C, Zhang X, Guo M, Sun M, Yu H, et al
