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and TNFa and IL-1 that cause secondary cascades

doi: 10.1007/s11033-025-10553-9

This facilitates a massive entry of substances into the intracellular system (e.g., K+, Ca2+, etc.), that could alter membrane proteins, enzymes and receptors ( Carbohydrates are also influenced by RONS with the formation of advanced glycation products (AGE) ( In addition, RONS alter DNA and RNA heterocyclic bases, in particular guanine: these alterations occur in Parkinsons disease (PD) affected brains

Monami M, Nreu B, Scatena A, Cresci B, Andreozzi F, Sesti G, et al

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