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Despite the numerous possible p53 mutations that exist, most studies with APR-246 have focused on the hotspot mutations, namely the conformational mutant R175H [10,11,12,13]

European Journal of Neuroscience 2004;19(6) 1494-1504

Nanocarrier facilitated drug delivery to the brain through intranasal route: a promising approach to transcend bio-obstacles and alleviate neurodegenerative conditions
DOI: 10.24412/2500-2295-2024-1-34-51 Aggarwal S., Dimitropoulou C., Lu Q., Black S.M., Sharma S

This corresponds to to * and n to * transitions, due to the peptide bond of an -helix