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Although metformin is a common drug for managing DM, however, monotherapy treatment with any antidiabetic drug will necessitate dosage increment since type 2 DM (T2DM) deteriorates over time due to the increasing pancreatic -cell dysfunction and will eventually require a combination therapy approach with another antidiabetic medication

Oral formsmay be used to treat gastrointestinal conditions, although the effectiveness of this method is less well studied

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