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Zhang, Y., Cao, H., Yu, Z., & Peng, Y

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Alterations in intestinal bacterial composition can increase intestinal permeability, which is associated with elevated levels of zonulin, a protein that regulates cell communication

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This leaky gut state not only disrupts intestinal homeostasis but also enables MPs, along with adsorbed toxicants such as heavy metals and persistent organic pollutants, to translocate into peripheral tissues and the central nervous system 36,77
