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Interestingly, several in vitro studies of experimentally induced G6PD-d in human monocytes and endothelial cells have demonstrated that exposure to hyperglycemia or free fatty acids alone, as seen in diabetes or hyperlipidemia, decrease G6PD activity

In CKD, damaged mitochondria are a convergence point for inflammatory pathways (Kang et al

34 In addition to the above pharmacological effects, Quercetin has antiviral, antibacterial, anti-fibrotic, anti-focal death, anti-obesity, antidepressant, and anti-aging properties, while inhibiting apoptosis, autophagy, and platelet aggregation, regulating the immune system, protecting against hyperlipidemia, hypertension, hyperglycemia, liver damage, and coronary artery disease

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