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267 Numerous HDACs exhibit redox regulation

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They found that among 46 -glutamyl peptides, glutathione (-glutamyl-cysteinyl-glycine) and -glutamyl-valinyl-glycine (-Glu-Val-Gly) were very strong calcium-sensing receptor (CaSR) agonists that increased the kokumi flavor of chicken consomm and enhanced sweet, salty, and umami tastes independently when added to aqueous solutions of sucrose, NaCl, and MSG, respectively, in human sensory tests

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Other important players mediating abnormal neuronal transmission in TLE are ligand-gated GABA and glutamate receptors

Cardiac dysfunctions were significantly alleviated in ASC- or caspase-1-deficient mice, or following silencing of either NLRP3 or P2X7, a pyroptosis stimulating ATP receptor [88, 129, 130]