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Betsuyaku T, Fuke S, Inomata T, et al
Vasoactive Intestinal Peptide (VIP) Improves blood-brain barrier integrity, reduces neuroinflammation
Prevents scurvy, an illness caused by a lack of vitamin C

An overview of the transsulfuration pathway is given in Figure 3

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However, observed barrier defects and associated diarrhea even in these mice did not result in changes in claudin-1, -2, -3, and -4 expression and cellular distributions, but rather correlated with the rearrangement of cellular distribution of occludin, and to some extent with JAM proteins