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Ferritinophagy activation and sideroflexin1-dependent mitochondria iron overload is involved in apelin-13-induced cardiomyocytes hypertrophy

These studies indicate that overproduction of glutathione drives the survival and growth of a small subset of lymphoid tumor cells in 3D gels and xenografts, likely TIC or TIC-like cells, and that glutathione is selectively required for tumor growth in females of a mouse model of lymphoma

Marek, Kenneth|Jennings, Danna|Lasch, Shirley|Siderowf, Andrew|Tanner, Caroline|Simuni, Tanya|Coffey, Chris|Kieburtz, Karl|Flagg, Emily|Chowdhury, Sohini|Poewe, Werner|Mollenhauer, Brit|Klinik, Paracelsus-Elena|Sherer, Todd|Frasier, Mark|Meunier, Claire|Rudolph, Alice|Casaceli, Cindy|Seibyl, John|Mendick, Susan|Schuff, Norbert|Zhang, Ying|Toga, Arthur|Crawford, Karen|Ansbach, Alison|De Blasio, Pasquale|Piovella, Michele|Trojanowski, John|Shaw, Les|Singleton, Andrew|Hawkins, Keith|Eberling, Jamie|Brooks, Deborah|Russell, David|Leary, Laura|Factor, Stewart|Sommerfeld, Barbara|Hogarth, Penelope|Pighetti, Emily|Williams, Karen|Standaert, David|Guthrie, Stephanie|Hauser, Robert|Delgado, Holly|Jankovic, Joseph|Hunter, Christine|Stern, Matthew|Tran, Baochan|Leverenz, Jim|Baca, Marne|Frank, Sam|Thomas, Cathi-Ann|Richard, Irene|Deeley, Cheryl|Rees, Linda|Sprenger, Fabienne|Lang, Elisabeth|Shill, Holly|Obradov, Sanja|Fernandez, Hubert|Winters, Adrienna|Berg, Daniela|Gauss, Katharina|Galasko, Douglas|Fontaine, Deborah|Mari, Zoltan|Gerstenhaber, Melissa|Brooks, David|Malloy, Sophie|Barone, Paolo|Longo, Katia|Comery, Tom|Ravina, Bernard|Grachev, Igor|Gallagher, Kim|Collins, Michelle|Widnell, Katherine L.|Ostrowizki, Suzanne|Fontoura, Paulo|Ho, Tony|Luthman, Johan|Brug, Marcel van der|Reith, Alastair D.|Taylor, Peggy The Parkinson Progression Marker Initiative (PPMI) Progress in Neurobiology [03010082]

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Therefore, the adverse effects of caffeine observed in stored RBC units are potentially also direct, mediated both through disrupted purinergic signaling (ADORA2b) and direct enzymatic inhibition (G6PD), in part mimicking the increased susceptibility to hemolysis and impaired post-transfusion survival of RBC from G6PD-deficient donors

Epub 2021 Aug 22