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28, 591606.10.1016/j.mam.2007.01.004 218 RiedererP.SoficE.RauschW

In their study, Vilela et al

AFBO can induce oxidative stress, bind to DNA and proteins, and contribute to hepatocarcinoma development by causing mutations in genes such as the p53 tumor suppressor gene [38]

The objective of this study was to evaluate the therapeutic activity of transient FAP-targeted CAR-T (FAPCAR-T) cells generated in vivo via a novelly designed LNP-mRNA system and the lung regeneration mechanism in a mouse model of bleomycin (BLM)-induced pulmonary fibrosis

100 mol/L DFO

p62, enriched in chromatin, directly interacts with the key enzyme APE1 in the BER pathway, enhancing its endonuclease activity and thereby promoting BER and cell survival [40]