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Optic nerve injection of lysophosphatidylcholine (LPC) induced localized myelin loss in MS mice, significantly elevating Fe 2+ and MDA levels, while reducing GSH, NRF2, and GPX4 expression, as well as iron reactive element binding protein 2 (IREB2) in optic nerve tissue

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Foy CJ, Passmore AP, Vahidassr MD, Young IS, Lawson JT (1999) Plasma chain-breaking antioxidants in Alzheimers disease, vascular dementia and Parkinsons disease