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Since ROS-dependent DNA damage is markedly increased in myeloid cells after Bcr-Abl transformation 18 , we hypothesize that blocking dTTP and dCTP supply might exacerbate replication stress and DNA damage in Bcr-Abl-transformed cells, thereby jeopardizing cell survival

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[DOI] [PubMed] [Google Scholar] 48.Zheng H., Wei J., Wang L., Wang Q., Zhao J., Chen S., Wei F., Kennedy D.A