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When NNMT is inhibited: NAD+ levels rise Mitochondria become more efficient Cells burn more energy, even at rest This effect helps the body shift into a more metabolically active state, making it easier to reduce fat and preserve muscle during weight loss

Nutrition: Keep protein intake adequate and overall diet balanced to support metabolism and lean mass

A shortage of vitamin B12 can lead to fatigue, weakness, diarrhea, and other symptoms

You can speak to the doctor and get a blood test to check your levels of B12

NNMT dysregulation is implicated across obesity, insulin resistance, liver pathology, and other disorders

These appear consistently at or near the top of national prescription lists