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doi: 10.3390/ijms241914857 18

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In conclusion, oxidative stress can be a possible explanation of hepatic damage induced by chronic therapy with chlorpheniramine maleate and cetirizine hydrochloride

Very recently, a study shows itaconate is required for the activation of the anti-inflammatory transcription factor Nrf2 (also known as NFE2L2) by lipopolysaccharide in mouse and human macrophages via dicarboxylation of KEAP1 (Mills et al., 2018)

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