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For instance, curcumin decreased the free light-chain ratio (rFLC), urinary deoxypyridinoline (uDPYD), the difference between clonal and non-clonal light-chain (dFLC), involved free light-chain (iFLC), and creatinine levels in patients with monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma

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For each tissue type, primary functions are mapped to their underlying molecular mechanisms and subsequent physiological impacts, revealing the complex interplay between local tissue activities and systemic metabolic regulation

doi: 10.1212/WNL.0000000000201289