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Influence of the 5-HT(3) receptor antagonist ondansetron on gastric sensorimotor function and nutrient tolerance in healthy volunteers

Purity was independently confirmed in-house by HPLC prior to use

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Both groups experienced improvement and there was no meaningful difference between oral and sublingual methods

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Ten years ago, our group validated this technique to assess esophageal mucosal integrity by showing a correlation to ex vivo measurements and a decrease after esophageal perfusion with acidic solutions (52)