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The GCLM subunit has no enzymatic activity but has an important regulatory function increasing the efficiency of the GCLC subunit
It is extensively metabolized to form the active metabolite, GFT1007 (M3), the mean systemic exposure (AUC) of which was 2 to 4-fold higher than that of the parent drug at steady state [7]
Int Rev Cell Mol Biol

10.3390/antiox8090413 [DOI] [PMC free article] [PubMed] [Google Scholar] Lassmann H

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