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One possible hypothesis is based on the ability of the SARS-CoV-2 virus to cross the blood-brain barrier and reach the brain, or that the virus may reach the brain via the hematogenous route 11

As the patient was exhausted by a few months of outpatient treatment, we had a discussion about the treatment policy with a doctor specializing in infectious diseases, including whether or not to switch to oral medicine

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Among the great variety of CPPs, penetratin was reported to be effective in the nose-to-brain delivery of antidiabetic peptides, including insulin and exendin-4, in an animal model of AD (Table 3)

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