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Many representative polyphenols and their analogues do not fully possess the properties necessary for ideal drug candidates, which include insufficient chemical stability, low water solubility, low efficacy and selectivity for target action, poor distribution in multiple tissues, unstable metabolic processes, and relatively high toxicity

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Progression to T2D is associated with higher pre-pregnancy BMI, advanced maternal age, family history of diabetes and postpartum lifestyle factors (154)

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Conclusion While L-carnitine shows promise as a potential aid in weight loss, more research should be done to confirm its effectiveness

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