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Description
These effects are uncommon and usually transient
[397] found a significantly increased accumulation of dysfunctional mitochondria in the fibroblasts isolated from SLOS patients under steady-state conditions compared to control cells

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Typically, glutathione within the mitochondria is maintained at a high level

Leukemia and Lymphoma 49(12):2246-2255, 2008

Without adequate levels, you may experience fatigue, weakness, and other related symptoms